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Final Program


Program-At-A-Glance

Hsin-Jung (Randy) Yang, PhD

Associate Professor
Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA
Los Angeles, California, United States

Hsin-Jung (Randy) Yang, PhD is an Associate Professor and Director of the Cardiac Imaging Research Program at the Biomedical Imaging Research Institute, Cedars-Sinai Medical Center. His research centers on the technical development of physiology-specific, quantitative cardiac MRI (CMR) methods to noninvasively interrogate myocardial metabolism, oxygen utilization, and energetic efficiency, with the goal of enabling mechanistic insight and precision monitoring of cardiovascular disease and therapy.

Dr. Yang has made sustained contributions to cardiac oxygenation and metabolism imaging, advancing oxygen-sensitive MRI techniques that allow direct, noninvasive assessment of myocardial oxygenation, oxygen extraction, and metabolic efficiency. His work has helped establish motion-robust T2*/BOLD imaging and coronary sinus oximetry as practical tools for probing myocardial oxygen metabolism without contrast agents, ionizing radiation, or invasive procedures.

A defining aspect of his program is the development of enabling CMR technologies that make physiological measurements reliable in the moving human heart. He has led innovations in free-running and motion-resolved acquisitions, advanced reconstruction frameworks, field-inhomogeneity-robust imaging, quantitative susceptibility mapping (QSM), and B₀ field control strategies. These technical advances directly improve image fidelity, quantitative accuracy, and reproducibility, forming the foundation for robust metabolic and tissue characterization.

Dr. Yang’s research spans MRI physics, sequence and reconstruction development, translational validation, and first-in-human clinical studies, enabling rapid translation of technical innovation into clinically meaningful imaging biomarkers. His work has been continuously supported by NIH funding and has generated multiple patentable technologies in cardiac MRI hardware, acquisition strategies, and quantitative analysis.

Through this integrated technical-physiological approach, Dr. Yang aims to transform cardiac MRI from a primarily descriptive modality into a quantitative, physiology-driven imaging platform for understanding disease mechanisms and guiding metabolic therapies.

Presentation(s):